Background on Creative PEGWorks website - leading PEG supplier.

Blogs

The Stealth Properties of PEG-Coated Nanoparticles are Dependent on the PEG Grafting Densities

The Lai lab at UNC Chapel Hill published an article in Molecular Pharmaceiuticals – Evading Immune Cell Uptake and Clearance Requires PEG Grafting at Densities Substantially Exceeding the Minimum for Brush Conformation. Mol. Pharmaceutics, 2014, 11 (4), pp 1250–1258, DOI: 10.1021/mp400703d. Exploration in PEG GraftingThis paper critically pointed out: Coating nanoparticles with polyethylene glycol (PEG), […]

Blogs

How Pegylated Drugs are Aiding Rheumatology

PEG Therapy Since PEG molecules bind to amino acids to target proteins, they are now being used in the Rheumatology field. For patients with Rheumatoid Arthritis who do not respond to standard treatment, the use of TNF-a inhibitors have been used as an alternative treatment. Positive signs with using this alternative treatment with a reduction […]

Blogs

FDA-Approved PEGylated Drugs

To date, only eleven PEGylated proteins, antibody fragments, oligonucleotides, and small molecules that have been approved by the FDA are on the market. Available PEGylated DrugsThis includes PEGylated bovine adenosine deaminase: pegademase bovine (Adagen); and PEGylated l-asparaginase: pegaspargase (Oncaspar); PEGylated products of interferon-alpha (IFN-alpha): peginterferon-2b (PegIntron) and peginterferon-2a (Pegasys); PEGylated granulocyte colony stimulating factor (GCSF): […]

Categories

PEGylation Reagents Available on Amazon!

Order PEG Products OnlineCreative PEGWorks set up a Merchant account on amazon.com to make the purchase of PEG products and PEG derivatives easier and faster. You can take advantage of your existing Amazon customer account to directly place orders!On amazon.com, customers can also place orders for other biopolymer products offered by Creative PEGWorks including hyaluronic […]

Blogs

What is Chitosan and How Do We Use it?

Polysaccharide Product It turns out that shellfish are much more than delicious appetizers or entrees at our seafood restaurant. Scientists can take sugar from the hard outer skeleton of shellfish, including crab, lobster, and shrimp and use it in medicine! This sugar is called chitosan, and it has a variety of great uses. It can […]

Blogs

Important Applications For Quantum Dots

Quantum Dots Semiconductor nanocrystals, also known as quantum dots, have a wide range of applications for many industries. Two of the most important applications for them are ink and in the medical industry. The particles emit distinctly different colors when they are reduced in size, and can be incorporated in materials as a sort of […]

Blogs

How PEGylation can help Growth Hormone Deficiency (GHD)

Pegylation Pegylation has achieved reasonable success on the market thus far: approximately one dozen PEGylated pharmaceuticals are currently on the market with FDA approval. One of those has been instrumental in fighting the deleterious effects of Growth Hormone Deficiency. Peg acrylate More commonly recognized as a banned substance in professional sports, Human Growth Hormone (HGH) […]

Blogs

The Future of Medicine: Tissue Engineering

Natural Polysaccharides One of the most exciting fields of medicine today is not on the direct patient contact side of the aisle. The research that is being done using Natural polysaccharides and carbohydrates is bound to change the world of modern medicine for good. Many of the changes that will erupt have yet to be […]

Blogs

3 Things To Know About Biopolymers

What Is a Biopolymer?A biopolymer is a polymer produced by living organisms, such as DNA and proteins, that are made of repetitive units called monomers.Where Are Biopolymers Found?Biopolymers are essential to every living organism. For example, cellulose, a biopolymer, is the most common organic compound on Earth and accounts for 33% of all plant matter.How […]

Blogs

Skin Penetrating Peptides Enhance Transdermal Delivery of Hyaluronic Acid

Hyaluronic acid (HA) is involved in various biologic processes such as hydration, nutrient exchange, and cell differentiation and motility. Hyaluronic acid is a major component of the skin’s extracellular matrix. Topical Delivery of Hyaluronic AcidFrequently, due to its high molecular weight and charge, HA is a difficult molecule to deliver into the skin. A joint […]

Blogs