Thiolated PEG can stabilize and also destabilize gold nanoparticles

PEG reagents are commonly used to prepare stable colloidal metal nanoparticle dispersion such as gold and silver through PEG thiol chemistry among other pegylation strategies. It typically works by replacing citrate or other capping ligands.

Did you know? By controlling the ratio of PEG-SH reagents to AuNP, you may get very stable, well dispersed AuNP solution; or you may get highly porous gold sponge! Gold sponge is a novel material where individual Au nanoparticles are self-assembled mediated by a reduction of negative zeta potential. Read the full article.

PEG may be able to do more than you can imagine!