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PEGylation Reagents

Fluorescent or Radioactive PEG-like Nanoprobes

Researchers from the Massachusetts General Hospital and Harvard Medical School developed the novel, “PEG-like Nanoprobes,’’ with controllable pharmacokinetics and tunable fluorescence. The “PEG-like Nanoprobes’’ nanoparticles feature a unique design where a single PEG polymer surrounds a short fluorochrome and radiometal bearing peptide, and endows the resulting nanoprobe with pharmacokinetic control (based on the molecular weight […]

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Designer Proteins Trigger Cell Death – a new cancer therapy?

Researchers from the University of Washington and the Howard Hughes Medical Institute use an innovative computational design approach coupled with in-vitro-targeted evolution to produce a potent polypeptide inhibitor that triggers apoptosis of virus-infected cancer cells, suppresses tumor growth, and extends survival in a xenograft model of EBV-positive human lymphoma. How Designer Proteins Impact Cancer Research […]

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