Catalog No. : PBL-266
Product Name : mPEG-Amine, MW 1k
Description :

mPEG-Amine is a linear methoxy PEG reagent with a reactive primary amine or NH2 group that can rapidly react with activated carboxyl acid such as NHS ester to form stable amide bonds. Amine can also react with carbonyl such as ketone and aldehyde. mPEG-Amine with MW at 1k or higher appears as white powder and at lower MW (e.g. 550 and 350) appears as white or off-white semi-solid or wax-like due to their low melting/freezing temperature range (e.g. mPEG MW 550 at 15-25 Celsius).

References:

1. Charles M Lieber et al, Specific detection of biomolecules in physiological solutions using graphene transistor biosensors, Proc. Natl. Acad. Sci. USA, DOI 10.1073/pnas.1625010114, 2016, Text.

2. Design and demonstration of a small-animal upconversion imager, Opt Express. 2008 December 22; 16(26): 21731–21737, Text.

3. Fluorescence Single Particle Tracking for the Characterization of Submicron Protein Aggregates in Biological Fluids and Complex Formulations, Pharm Res (2011) 28:1112–1120, Text.

4. Characterization of hydrogel microstructure using laser tweezers particle tracking and confocal reflection imaging, J Phys Condens Matter. 2010; 22(19): 194121, Text.

5. Ex vivo characterization of particle transport in mucus secretions coating freshly excised mucosal tissues, Mol Pharm. 2013 June 3; 10(6): 2176–2182, Text.

6. Nanoparticle diffusion in respiratory mucus from humans without lung disease, Biomaterials. 2013 April ; 34(13): 3439–3446, Text.

7. Convection enhanced delivery of cisplatin-loaded brain penetrating nanoparticles cures malignant glioma in rats, J. Controlled Release, 2017, 263, 112-119, Text.

8. MR image-guided delivery of cisplatin-loaded brain-penetrating nanoparticles to invasive glioma with focused ultrasound, Journal of Controlled Release, Volume 263, 10 October 2017, Pages 120-131. Text.

9. Blood component ridable and CD44 receptor targetable nanoparticles based on a maleimide-functionalized chondroitin sulfate derivative, Carbohydrate Polymers, 2019, 115568, Text.

10. Positron emission tomography imaging of novel AAV capsids maps rapid brain accumulation, Nature Communications, 2020, DOI: 10.1038/s41467-020-15818-4

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