Description
mPEG-O-C12 is a linear methoxy PEG with one C12 alkyl through an ether bond. The polyethylene glycol dodecyl ether is an amphiphilic, surfactant-like polymer. PEG surfactant is useful to form micelles, drug delivery systems to enhance drug solubility and improve formulation and bioavailability. mPEG attached to C12 via amide bond or hydrolytic ester bonds are available, please contact us.
Properties
Molecular weight: MW of PEG was measured by MALDI-MS or GPC. PDI (polydispersity index) of our linear PEG is 1.02-1.05 with very narrow MW distribution. The number of repeating ethylene oxide units (CH2CH2O) or the degree of polymerization is calculated dividing the PEG MW by 44 (44 is the molecular mass of one repeating unit).
Solubility: Soluble in water and aqueous buffer, chloroform, methylene chloride, DMF, DMSO, and less soluble in alcohol, toluene. Not soluble in ether.
Density: PEG density is approximately 1.125 g/mL
Physical form: PEG products generally appear as white or off-white powder, and for very low MW linear PEG such as MW 1k or less, it may appear as wax-like, semi-solid material due to the low MW and the type of functional groups.
Storage condition: PEG product shall be stored in the original form as received in a freezer at -20C or lower for long term storage. Stock solution of PEG reagents that do not contain oxygen or moisture sensitive functional groups may be temporarily stored in a refrigerator or ambient temperature for multiple days. Stock solution should avoid repeated freeze-and-thaw cycles. See Documents section for detailed storage and handling conditions.
References
1. Thomas SW. Polymer Amphiphiles for Photoregulated Anticancer Drug Delivery. ACS Applied Materials & Interfaces. 2018 Dec 24. Text.
2. Supramolecular polymers form tactoids through liquid–liquid phase separation, Nature, volume 626, pages 1011–1018 (2024), Text.
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