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mPEG-alkyne is a linear monofunctional PEG reagent with a reactive alkyne or acetylene. PEG-Alkyne is useful for PEGylation via a click chemistry reaction with azide.
mPEG-Alkyne, MW 2k
mPEG-Alkyne, MW 2k
SKUProduct Name
PLS-2035-10g
mPEG-Alkyne, MW 2k - 10g
$1,350.00
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PLS-2035-5g
mPEG-Alkyne, MW 2k - 5g
$900.00
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PLS-2035-1g
mPEG-Alkyne, MW 2k - 1g
$300.00
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Properties
Molecular weight: MW of PEG was measured by MALDI-MS or GPC. PDI (polydispersity index) of our linear PEG is 1.02-1.05 with very narrow MW distribution. The number of repeating ethylene oxide units (CH2CH2O) or the degree of polymerization is calculated dividing the PEG MW by 44 (44 is the molecular mass of one repeating unit).
Solubility: Soluble in water and aqueous buffer, chloroform, methylene chloride, DMF, DMSO, and less soluble in alcohol, toluene. Not soluble in ether.
Density: PEG density is approximately 1.125 g/mL
Physical form: PEG products generally appear as white or off-white powder, and for very low MW linear PEG such as MW 1k or less, it may appear as wax-like, semi-solid material due to the low MW and the type of functional groups.
Storage condition: PEG product shall be stored in the original form as received in a freezer at -20C or lower for long term storage. Stock solution of PEG reagents that do not contain oxygen or moisture sensitive functional groups may be temporarily stored in a refrigerator or ambient temperature for multiple days. Stock solution should avoid repeated freeze-and-thaw cycles. See Documents section for detailed storage and handling conditions.
References
1. Clickable PEGylation of Proteins – Identification and Origin of N-Linked b-D-NAcetylglucosamine Monosaccharide Modifications on Arabidopsis Proteins. Plant Physiology, 2013, 161: 455–464, Text.
2. Visualization of O†GlcNAc Glycosylation Stoichiometry and Dynamics Using Resolvable Poly(ethylene glycol) Mass Tags, Current Protocols in Chemical Biology, 5:281–302,Text.
3. Surface functionalization of virus-like particles by direct conjugation using azide-alkyne click chemistry. Bioconjugate chemistry 22.3 (2011): 376-387. Text
4. Methods for the Detection, Study, and Dynamic Profiling of O-GlcNAc Glycosylation, Methods in Enzymology, 2017, doi: 10.1016/bs.mie.2017.06.009, Text.
5. O-GlcNAc glycosylation stoichiometry of the FET protein family: only EWS is glycosylated with a high stoichiometry, DOI: 10.1080/09168451.2016.1263148, Text.
6. Synthesis of biocompatible polymeric nanomaterial dually loaded with paclitaxel and nitric oxide for anti-MDR cancer therapy, RSC Adv., 2016, 6, 105871-105877, Text.
7. A novel phosphoester-based cationic co-polymer nanocarrier delivers chimeric antigen receptor plasmid and exhibits anti-tumor effect. RSC Advances 8.27 (2018): 14975-14982. Text.
8. O-GlcNAcylation of PERIOD regulates its interaction with CLOCK and timing of circadian transcriptional repression, PLoS Genet 15(1): e1007953, 10.1371/journal.pgen.1007953
9. Carbon dioxide sorption and melting behaviour of mPEG-alkyne, The Journal of Supercritical Fluids 171 (2021) 105182, Text.
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