8-Arm PEG-OH is a multi-armed polyethylene glycol with hydroxyl groups at each terminal of the eight arms. One hexaglycerol core connects all eight branched arms. The indicated molecular weight of multi-arm PEG is the sum of the molecular weights of all arms. The MW of each arm is one eighth (1/8) of the indicated MW.
Molecular weight: 8-Arm PEG MW refers to the MW of the entire PEG molecule. The MW of each arm is 1/8 of the MW indicated in the product name. MW of PEG was measured by MALDI-MS or GPC. PDI (polydispersity index) of our 8-Arm PEG is 1.02-1.06 with very narrow MW distribution. The number of repeating ethylene oxide units (CH2CH2O) or the degree of polymerization is calculated dividing the PEG MW by 44 (44 is the molecular mass of one repeating unit).
Solubility: Soluble in water and aqueous buffer, chloroform, methylene chloride, DMF, DMSO, and less soluble in alcohol, toluene. Not soluble in ether.
Density: PEG density is approximately 1.125 g/mL
Physical form: PEG products generally appear as white or off-white powder, and for certain special 8-arm PEGs, it may appear as wax-like, semi-solid material due to low MW and the type of functional groups.
Storage condition: PEG product shall be stored in the original form as received in a freezer at -20C or lower for long term storage. Stock solution of PEG reagents that do not contain oxygen or moisture sensitive functional groups may be temporarily stored in a refrigerator or ambient temperature for multiple days. Stock solution should avoid repeated freeze-and-thaw cycles. See Documents section for detailed storage and handling conditions.
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2. Ultralow protein adsorbing coatings from clickable PEG nanogel solutions: Benefits of attachment under salt-induced phase separation conditions and comparison with PEG/albumin nanogel coatings. Langmuir 29.12 (2013): 4128-4139. Text.
3. Nanogel surface coatings for improved single-molecule imaging substrates. Journal of The Royal Society Interface 8.63 (2011): 1400-1408. Text.
4. Digital Protein Analysis: Technologies for Protein Diagnostics and Proteomics through Single-Molecule Detection. (2011) Text.
5. Multivalency enables dynamic supramolecular host-guest hydrogel formation, Biomacromolecules 2020, Text.
6. Efficiency range of the BelousovÃ¢â‚¬“Zhabotinsky reaction to induce the self-organization of transient bonds in metallo-supramolecular polymeric systems, Phys. Chem. Chem. Phys., 2020, doi: 10.1039/D0CP02429E
7. Antioxidant shape amphiphiles for accelerated wound healing, J. Mater. Chem. B, 2020, DOI: 10.1039/D0TB00578A
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