4-Arm PEG-Tyramine / Catechol / Dopamine

Description

4-Arm PEG-Dopamine has 4 dopamine molecules attached to the four arms through an amide bond. Essentially, catechol is attached PEG via amide bond formed between the amine of dopamine and acid of PEG. Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is a neuromodulatory molecule that plays several important roles in cells. It is an organic chemical of the catecholamine and phenethylamine families. On the chemical side, polydopamine is polymerized dopamine that is formed from a slightly basic dopamine solution in the presence of oxygen, and it is a bioinspired material from adhesive polyphenolic proteins in mussels. Similarly, 4-Arm PEG-Phenol has 4 phenol groups attached to the PEG at its para or 4-position of the benzene ring, via amide bonds between the amine of tyramine and acid of PEG.