Mono-Biotin Labeled Hyaluronan, MW 5k

Mono-Biotin Labeled Hyaluronan, MW 5k

Catalog No:HA-620
Product Name:Mono-Biotin Labeled Hyaluronan, MW 5k
In Stock: Yes
SKUProduct Name
HA-620-50mg
Mono-Biotin Labeled Hyaluronan, MW 5k - 50mg
$950.00
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+
HA-620-100mg
Mono-Biotin Labeled Hyaluronan, MW 5k - 100mg
$1,450.00
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+
HA-620-10mg
Mono-Biotin Labeled Hyaluronan, MW 5k - 10mg
$450.00
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+
Interested in Bulk Orders? Please contact us here

Description

Mono-Biotin Labeled Hyaluronan has one single biotin molecule at the reducing end of HA polymer. Purity: >95% lyophilized powder. Degree of substitution: one biotin molecule per HA polymer. Hyaluronic Acid synonyms: HA, hyaluronate, hyaluronan.

Properties

Name and Source: Hyaluronic acid (HA, Hyaluronan, Hyaluronate) is an anionic, non-sulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. CAS# 9004-61-9. Our HA products are produced via microbial fermentation. See Documents section for details.

Appearance: White, lyophilized powder, except dye-labeled HA reagents.

Solubility: Soluble in water and the solubility data varies with MW. Higher MW results in lowered solubility. Typically solubility ranges 5-50 mg/mL, that is, 0.5%-5%. Buffered solution at pH >6 enhances solubility due to deprotonation of carboxylic acid groups and formation of carboxylate salts. HA derivatives with hydrophobic groups will lower the solubility in water, and adding alcohol or DMSO to an alcohol-water or DMSO-water mixture can dramatically improve the solubility up to 200 mg/mL (20%).

References

1. Structural basis of laminin binding to the LARGE glycans on dystroglycan, Nature Chemical Biology12,810(2016), Text.

2. Clearance kinetics of biomaterials affects stem cell retention and therapeutic efficacy.  Biomacromolecules 15.2 (2014): 564-573. Text.

3. Biotinylated hyaluronic acid: a new tool for probing hyaluronate-receptor interactions. Bioconjug Chem., 1994, 5(4):370-2.

4. 3. Single-molecule mechanical measurements of the hyaluronan-aggrecan bottle brush, Biomolecules, 2019, arXiv:1910.13576

Click here to view an expanded list of hundreds of publications citing Creative PEGWorks products.

Documents

 Technical Information Hyaluronic Acid Products
 SDS of Mono-Biotin Labeled Hyaluronan

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