Background on Creative PEGWorks website - leading PEG supplier.

Mono-Biotin Labeled Hyaluronan, MW 20k

Mono-Biotin Labeled Hyaluronan, MW 20k

Catalog No: HA-622
Product Name: Mono-Biotin Labeled Hyaluronan, MW 20k
In Stock: Yes
SKUProduct Name
HA-622-10mg
Mono-Biotin Labeled Hyaluronan, MW 20k - 10mg
$250.00
-
+
HA-622-50mg
Mono-Biotin Labeled Hyaluronan, MW 20k - 50mg
$750.00
-
+
HA-622-100mg
Mono-Biotin Labeled Hyaluronan, MW 20k - 100mg
$1,150.00
-
+
Interested in Bulk Orders? Please contact us here

Description

Mono-Biotin Labeled Hyaluronan has one single biotin molecule at the reducing end of HA polymer. Purity: >95% lyophilized powder. Degree of substitution: one biotin molecule per HA polymer. Hyaluronic Acid synonyms: HA, hyaluronate, hyaluronan.

Properties

Name and Source: Hyaluronic acid (HA, Hyaluronan, Hyaluronate) is an anionic, non-sulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. CAS# 9004-61-9. Our HA products are produced via microbial fermentation. See Documents section for details.

Appearance: White, lyophilized powder, except dye-labeled HA reagents.

Solubility: Soluble in water and the solubility data varies with MW. Higher MW results in lowered solubility. Typically solubility ranges 5-50 mg/mL, that is, 0.5%-5%. Buffered solution at pH >6 enhances solubility due to deprotonation of carboxylic acid groups and formation of carboxylate salts. HA derivatives with hydrophobic groups will lower the solubility in water, and adding alcohol or DMSO to an alcohol-water or DMSO-water mixture can dramatically improve the solubility up to 200 mg/mL (20%).

References

1. Structural basis of laminin binding to the LARGE glycans on dystroglycan, Nature Chemical Biology12,810(2016), Text.

2. Clearance kinetics of biomaterials affects stem cell retention and therapeutic efficacy.   Biomacromolecules 15.2 (2014): 564-573.  Text.

3. Biotinylated hyaluronic acid: a new tool for probing hyaluronate-receptor interactions. Bioconjug Chem., 1994, 5(4):370-2.

4. 3. Single-molecule mechanical measurements of the hyaluronan-aggrecan bottle brush, Biomolecules, 2019, arXiv:1910.13576

Click here  to view an expanded list of hundreds of publications citing Creative PEGWorks products.

Documents

 Technical Information Hyaluronic Acid Products
 SDS of Mono-Biotin Labeled Hyaluronan

Get In Touch

If you have any questions, please submit an online inquiry.

"*" indicates required fields

Your Name*
Do you wish to receive emails for new product introduction and sale promotions?
By submitting this form, you are consenting to our privacy policy.
This field is for validation purposes and should be left unchanged.