Heparin Thiol is a reactive heparin polysaccharide for bioconjugation or crosslinking. Heparin has functionalized thiol groups. Thiol groups react with maleimide via thiol-ene reactions. Heparin thiols is also useful to prepare heparin hydrogels by thiol-thiol crosslinking reaction. To maximize the reactivity of thiols, a reducing reagent TECP may be helpful. Purity: >95% lyophilized powder. Standard degree of substitution: 5 mol % substitution. Heparin-Thiol derivatives with lower or higher thiol SH substitution ratio (e.g. 1% and 10%) is available through custom synthesis service.