Heparin Fluorescein, MW 27k
Heparin Fluorescein is a fluorescent heparin polysaccharide. Heparin is functionalized with fluorescein (FITC), Ex/Em wavelength 494/518 nm. Purity: >95% powder. Degree of substitution: 1 mol % substitution and at least one dye molecule per polymer. Higher fluorescein substitution such as 5% is available through custom synthesis.
Heparin is a member of the glycosaminoglycan family of carbohydrates (which includes the closely related molecule heparan sulfate) and consists of a variably sulfated repeating disaccharide unit. The most common disaccharide unit in heparin is composed of a 2-O-sulfated iduronic acid and 6-O-sulfated, N-sulfated glucosamine, IdoA(2S)-GlcNS(6S).
Heparin CAS#: 9005-49-6
1. Enhanced articular cartilage by human mesenchymal stem cells in enzymatically mediated transiently RGDS-functionalized collagen-mimetic hydrogels, Acta Biomaterialia, 2017, 51, 75-88, Text.
2. Preparation and properties of biologically active fluorescent heparins, Biochimica et biophysica acta, 1978, 544(2), 430-40.
3. NPM1 exhibits structural and dynamic heterogeneity upon phase separation with the p14ARF tumor suppressor, Journal of Magnetic Resonance, 310, 2020, 106646, doi: 10.1016/j.jmr.2019.106646
4. A Pumpless Microfluidic Neonatal Lung Assist Device for Support of Preterm Neonates in Respiratory Distress, bioRxiv, 2020, 10.1101/2020.02.22.961102
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