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Heparin Biotin, MW 27k

Heparin Biotin, MW 27k

Catalog No: HP-207
Product Name: Heparin Biotin, MW 27k
In Stock: Yes
SKUProduct Name
HP-207-100mg
Heparin Biotin, MW 27k - 100mg
$1,050.00
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HP-207-10mg
Heparin Biotin, MW 27k - 10mg
$200.00
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HP-207-50mg
Heparin Biotin, MW 27k - 50mg
$600.00
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Interested in Bulk Orders? Please contact us here

Description

Heparin is functionalized with biotin. Purity: >95% lyophilized powder. Standard degree of substitution: 1 mol % substitution and at least one biotin molecule per heparin polymer. Higher biotin substitution such as 2% and 5% is available by custom synthesis service.

Properties

Heparin is a member of the glycosaminoglycan family of carbohydrates  (which includes the closely related molecule  heparan sulfate) and consists of a variably sulfated repeating  disaccharide unit. The most common disaccharide unit in heparin is composed of a 2-O-sulfated iduronic acid  and 6-O-sulfated, N-sulfated glucosamine, IdoA(2S)-GlcNS(6S).

Heparin CAS#: 9005-49-6

References

1)  Chikungunya virus strains from each genetic clade bind sulfated glycosaminoglycans as attachment factors, J Virol,2020, Text.

2) Detection of receptors for sulfated polysaccharides in human placenta by biotinylated probes, Journal of Histochemistry and Cytochemistry, 1988, 36(9):1097-102.

3)  Specific Inhibition of Heparanase by Glycopolymer with Well-Defined Sulfation Pattern Prevents Breast Cancer Metastasis in Mice. ACS Applied Materials & Interfaces. 2018 Dec 13.  Text  .

Documents

 Technical Information_Polysaccharide Products
 SDS of Heparin Biotin

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