Heparin is functionalized with amine groups. Purity: >95% powder. Standard Degree of substitution (DoS): 5 mol % substitution. Heparin-Amine derivatives with lower or higher amine NH2 substitution ratio (e.g. 1% and 10%) is available via custom synthesis.
Heparin is a member of the glycosaminoglycan family of carbohydrates (which includes the closely related molecule heparan sulfate) and consists of a variably sulfated repeating disaccharide unit. The most common disaccharide unit in heparin is composed of a 2-O-sulfated iduronic acid and 6-O-sulfated, N-sulfated glucosamine, IdoA(2S)-GlcNS(6S).
Heparin CAS#: 9005-49-6
1) Selective N-desulfation of heparin with dimethyl sulfoxide containing water or methanol, Curbohydrate Research, 1976, 46 (1):87-95