Chondroitin Sulfate Rhodamine is a fluorescently labeled polysaccharide. Chondroitin Sulfate is labeled with rhodamine via stable amide bond, Ex/Em wavelength 552/575 nm. Purity: >95% powder. Degree of substitution: 1 mol % substitution and at least one dye molecule per polymer. CS labeled with other types of rhodamine dyes such as Texas Red, Sulforhodamine 101 may be offered through our custom synthesis.
Chondroitin sulfate chains are unbranched polysaccharides containing two alternating monosaccharides: D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc). Chondroitin sulfate from terrestrial animals is almost exclusively composed of non-sulfated (O) and monosulfated (A and C) units, while in marine species the proportion of disulfated (D and E) units is higher. Chondroitin sulfate A is sulfated at carbon 4 of the N-acetylgalactosamine (GalNAc) sugar, also called chondroitin-4-sulfate
Chondroitin sulfate is highly soluble in water.
1) Role of the cytoskeleton in growth cone motility and axonal elongation, Neuroscience, 1996, 8(2):67-80;
2) Preparation and properties of fluorescent glycosaminoglycuronans labeled with 5-aminofluorescein, Carbohydrate research, 1982, 105(1), 69-85