Chitosan Biotin, MW 200kDa, 85% DDA
Chitosan is labeled with biotin through an amide bond between the amine of chitosan and the carboxylic acid of biotin. Purity: >95% lyophilized powder. Standard Degree of substitution: 1 mol % substitution and at least one biotin molecule per Chitosan polymer. DDA: degree of deacetylation; cP: centipoise.
Chitosan is produced by deacetylation  of  chitin, which is the structural  element  in the  exoskeleton  of  crustaceans  (such as crabs and shrimp) and cell walls of  fungi. The degree of deacetylation (%DD) can be determined by  NMR spectroscopy from 60 to 100%.Chitosan products are characterized by either its MW or its viscosity.  The  amino  group in chitosan has a  pKa  value of ~6.5.
1) Intrinsic viscosity–molecular weight relationship for chitosan, Journal of Polymer Science: Part B: Polymer Physics, Vol. 38, 2591–2598 (2000), Text. Link.
2) Selective biotinylation of Neisseria meningitidis group B capsular polysaccharide and application in an improved ELISA for the detection of specific antibodies. J Immunol Methods. 1993, 160(1):35-47.
3) Avidin identification with polymer membrane-bound biotin, Kobunshi Ronbunshu, 1982, 39(10):587-92.
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