Catalog No. : PPE-201
Product Name : LPEI-b-PEG-b-LPEI, PEG 2k, PEI 2k
Description :

This product is a block copolymer of two linear PEI (LPEI) with one linear PEG, LPEI-b-PEG-b-LPEI. The MW indicated in the product refers to the MW of each PEI block.

PEG-b-PEI, copolymers of cationic poly(ethylene imine) (PEI) and polyethylene glycol (PEG) are well-studied compounds that markedly improve the in vitro and in vivo delivery of oligonucleotides and nucleic acids (DNA, siRNA). By varying the MW of PEI and PEG, PEG-PEI drug conjugates, polyplexes or nanoparticles can be prepared with a dynamic range of size, surface charge, and stability, which all are important to the transfection efficiency. PEG-b-PEI copolymers can be synthesized with customer specified MW.

References:

1. Synthesis of biocompatible polymeric nanomaterial dually loaded with paclitaxel and nitric oxide for anti-MDR cancer therapy, RSC Adv., 2016, 6, 105871-105877, Text.

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$380/100mg
$820/500mg
$1,160/1g
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