Background on Creative PEGWorks website - leading PEG supplier.

PLGA-PEG-NHS, custom synthesis any MW and L to G ratio

PLGA-PEG-NHS, custom synthesis any MW and L to G ratio

Catalog No: MTO-PLGAE
Product Name: PLGA-PEG-NHS, custom synthesis any MW and L to G ratio
In Stock: Yes
Interested in Bulk Orders? Please contact us here

Description

PLGA-PEG-NHS has a NHS ester group at the distal end of PEG block. The reagent is an amine-reactive amphiphilic AB diblock copolymer consisting of a hydrophilic block polyethylene glycol (PEG) and a hydrophobic block poly(lactide-co-glycolide) (PLGA). The hydrophobic block terminates with a hydroxyl group. PEGylated copolymers with biodegradable and biocompatible polyester segments can be useful to prepare core-shell micelles, nanoparticles and microspheres. The hydrolytic degradability of polyester segments depend on the molecular weight and the spacer between ester groups. PEG-PLGA with other MW and a variety of L to G ratio is also available.

Properties

PLGA – poly(lactide-co-glycolide) copolymer are available at a wide range of molecular weight (MW) and monomer (lactide to glycolide) ratios. PLGA can be dissolved in a wide range of solvents – higher lactide polymers can be dissolved using chlorinated solvents whereas higher glycolide polymers will require the use of fluorinated solvents such as hexafluoroisopropanol (HFIP) and perfluoroacetone.

References

1) Biodegradable long-circulating polymeric nanospheres. Science 1994;363:1600–3, Text.

Get In Touch

If you have any questions, please submit an online inquiry.

"*" indicates required fields

Your Name*
Do you wish to receive emails for new product introduction and sale promotions?
By submitting this form, you are consenting to our privacy policy.
This field is for validation purposes and should be left unchanged.