PLA-PEG-MAL, PLA 2k & PEG 2k

PLA-PEG-MAL, PLA 2k & PEG 2k

Catalog No:DL-2k2k-MAL
Product Name:PLA-PEG-MAL, PLA 2k & PEG 2k
In Stock: Yes
SKUProduct Name
DL-2k2k-MAL-1g
PLA-PEG-MAL, PLA 2k & PEG 2k - 1g
$1,450.00
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DL-2k2k-MAL-500mg
PLA-PEG-MAL, PLA 2k & PEG 2k - 500mg
$950.00
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DL-2k2k-MAL-100mg
PLA-PEG-MAL, PLA 2k & PEG 2k - 100mg
$350.00
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+
Interested in Bulk Orders? Please contact us here

Description

Maleimide functionalized PEG-PLA is a useful reagent to prepare core-shell nanoparticles with a thiol-reactive maleimide for conjugation with peptide or proteins bearing free thiols. PEG-PLA is an amphiphilic AB diblock copolymer consisting of a hydrophilic block polyethylene glycol (PEG) or polyethylene oxide (PEO) and a hydrophobic block polylactic acid or polylactide (PLA). The PEG polymer is capped a methyl ether group, and the hydrophobic block terminates with a hydroxyl group. PEGylated copolymers with biodegradable and biocompatible polyester segments can be used to prepare core-shell micelles, nanoparticles and microspheres.

References

1) Biodegradable long-circulating polymeric nanospheres. Science 1994;363:1600–3, Text.

2) Bioerodible Hydrogels Based on Photopolyrneried Poly(ethylene glycol)-co-poly(α-hydroxy acid) Diacrylate Macrorners, Macromolecules, 26, 1993: 581—537, Text.

Documents

 SDS of PLA-PEG-MAL

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