PEG-PCL, PEG MW 350 & PCL MW 1000

PEG-PCL, PEG MW 350 & PCL MW 1000

Catalog No:DC-3501k
Product Name:PEG-PCL, PEG MW 350 & PCL MW 1000
In Stock: Yes
SKUProduct Name
DC-3501k-5g
PEG-PCL, PEG MW 350 & PCL MW 1000 - 5g
$1,500.00
-
+
DC-3501k-500mg
PEG-PCL, PEG MW 350 & PCL MW 1000 - 500mg
$300.00
-
+
DC-3501k-1g
PEG-PCL, PEG MW 350 & PCL MW 1000 - 1g
$500.00
-
+
Interested in Bulk Orders? Please contact us here

Description

PEG-PCL is an amphiphilic block copolymer consisting of a hydrophilic polyethylene glycol (PEG) and a hydrophobic polycaprolactone (PCL). The PEG polymer is capped a methyl ether group (i.e. mPEG). The hydrophobic block terminates with a hydroxyl group. Biocompatible PEGylated copolymers with biodegradable polyester segments can be used to prepare core-shell micelles, nanoparticles and microspheres. The hydrolytic degradability of the polyester block depends on the molecular weight and the spacer between ester groups (lactide, glycotide or caprolactone). PEG-PCL with other MWs is also offered.

References

1) Site-Specific Addressing of Particles and Coatings via Enzyme-Mediated Destabilization, Catalysts 2019, 9, 354; doi:10.3390/catal9040354

2) Selective eradication of human non-small cell lung cancer cells using aptamer-decorated nanoparticles harboring a cytotoxic drug cargo, Cell Death & Disease, 10, 702 (2019), DOI: 10.1038/s41419-019-1870-0

3) Biodegradable long-circulating polymeric nanospheres. Science 1994;363:1600-3, Text.

4) Cyclic RGDfK- and Sulfo-Cy5.5-functionalized mPEG-PCL theranostic nanosystems for hepatocellular carcinoma, Journal of Industrial and Engineering Chemistry, 2021, 204-213, Text.

5) Long-acting tunable release of amlodipine loaded PEG-PCL micelles for tailored treatment of chronic hypertension, Nanomedicine: Nanotechnology, Biology and Medicine, 2021, 102417, Text.

Click here to view an expanded list of hundreds of publications citing Creative PEGWorks products.

Get In Touch

If you have any questions, please submit an online inquiry.

Your Name*
Do you wish to receive emails for new product introduction and sale promotions?
By submitting this form, you are consenting to our privacy policy.
This field is for validation purposes and should be left unchanged.