PEG-PCL, PEG MW 2000 & PCL MW 5000

PEG-PCL, PEG MW 2000 & PCL MW 5000

Catalog No:DC-2k5k
Product Name:PEG-PCL, PEG MW 2000 & PCL MW 5000
In Stock: Yes
SKUProduct Name
DC-2k5k-1g
PEG-PCL, PEG MW 2000 & PCL MW 5000 - 1g
$500.00
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DC-2k5k-5g
PEG-PCL, PEG MW 2000 & PCL MW 5000 - 5g
$1,500.00
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DC-2k5k-500mg
PEG-PCL, PEG MW 2000 & PCL MW 5000 - 500mg
$300.00
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+
Interested in Bulk Orders? Please contact us here

Description

PEG-PCL is an amphiphilic block copolymer consisting of a hydrophilic polyethylene glycol (PEG) and a hydrophobic polycaprolactone (PCL). The PEG polymer is capped a methyl ether group (i.e. mPEG). The hydrophobic block terminates with a hydroxyl group. Biocompatible PEGylated copolymers with biodegradable polyester segments can be used to prepare core-shell micelles, nanoparticles and microspheres. The hydrolytic degradability of the polyester block depends on the molecular weight and the spacer between ester groups (lactide, glycotide or caprolactone). PEG-PCL with other MWs is also offered.

References

1) Site-Specific Addressing of Particles and Coatings via Enzyme-Mediated Destabilization, Catalysts 2019, 9, 354; doi:10.3390/catal9040354

2) Selective eradication of human non-small cell lung cancer cells using aptamer-decorated nanoparticles harboring a cytotoxic drug cargo, Cell Death & Disease, 10, 702 (2019), DOI: 10.1038/s41419-019-1870-0

3) Biodegradable long-circulating polymeric nanospheres. Science 1994;363:1600-3, Text.

4) Cyclic RGDfK- and Sulfo-Cy5.5-functionalized mPEG-PCL theranostic nanosystems for hepatocellular carcinoma, Journal of Industrial and Engineering Chemistry, 2021, 204-213, Text.

5) Long-acting tunable release of amlodipine loaded PEG-PCL micelles for tailored treatment of chronic hypertension, Nanomedicine: Nanotechnology, Biology and Medicine, 2021, 102417, Text.

Click here to view an expanded list of hundreds of publications citing Creative PEGWorks products.

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