PEG-g-LPEI, PEG 2k, PEI 22k, PEG/PEI ratio 15

PEG-g-LPEI, PEG 2k, PEI 22k, PEG/PEI ratio 15

Catalog No:PPE-401
Product Name:PEG-g-LPEI, PEG 2k, PEI 22k, PEG/PEI ratio 15
In Stock: Yes
SKUProduct Name
PPE-401-500mg
PEG-g-LPEI, PEG 2k, PEI 22k, PEG/PEI ratio 15 - 500mg
$950.00
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PPE-401-100mg
PEG-g-LPEI, PEG 2k, PEI 22k, PEG/PEI ratio 15 - 100mg
$350.00
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PPE-401-1g
PEG-g-LPEI, PEG 2k, PEI 22k, PEG/PEI ratio 15 - 1g
$1,250.00
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+
Interested in Bulk Orders? Please contact us here

Description

PEG-g-LPEI is a graft copolymer of linear PEI with multiple PEGs. The PEG to PEI ratio is the average number of PEGs per PEI.  For 22,000 MW PEI, PEG/PEI ratio of 15 is roughly 3% of PEI units grafted with PEGs. Custom service is available for any MW of PEI and any MW of PEG at any graft ratio PEG-g(x)-PEI.

PEG-PEI, copolymers of cationic poly(ethylene imine) (PEI) and polyethylene glycol (PEG). The copolymer markedly improves the in vitro and in vivo delivery of oligonucleotides and nucleic acids (DNA, siRNA). By varying the MW of PEI and PEG, PEG-PEI drug conjugates, polyplexes or nanoparticles can be prepared with a dynamic range of size, surface charge, and stability, which all are important to the transfection efficiency in mRNA vaccine, gene delivery etc. PEG-PEI copolymers can be synthesized with customer specified MW.

References

1. Synthesis of biocompatible polymeric nanomaterial dually loaded with paclitaxel and nitric oxide for anti-MDR cancer therapy, RSC Adv., 2016, 6, 105871-105877Text.

2. Critical Length of PEG Grafts on LPEI/DNA Nanoparticles for Efficient in Vivo Delivery, ACS Biomater. Sci. Eng. 2016, 2, 567−578, Text.

Click here to view an expanded list of hundreds of publications citing Creative PEGWorks products.

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