Name: PCL-PEG-NH2, custom synthesis
SKU: MTO-PCLN
Availability: InStock

PCL-PEG-NH2, custom synthesis

Illustration of Amine PEG PCL for drug delivery.

Catalog No:	MTO-PCLN
Product Name:	PCL-PEG-NH2, custom synthesis
In Stock:	Yes

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Description

PCL-PEG-NH2 is an amphiphilic block copolymer consisting of a hydrophilic polyethylene glycol (PEG) and a hydrophobic polycaprolactone (PCL). The PEG polymer is capped a amine (amino) group, and the hydrophobic block terminates with a hydroxyl group.

Biocompatible PEGylated copolymers with biodegradable polyester segments can be used to prepare core-shell micelles, nanoparticles and microspheres. The hydrolytic degradability of the polyester block depends on the molecular weight and the spacer between ester groups (lactide, glycotide or caprolactone). PEG-PCL with other MWs is also offered.

References

1. Cyclic RGDfK- and Sulfo-Cy5.5-functionalized mPEG-PCL theranostic nanosystems for hepatocellular carcinoma, Journal of Industrial and Engineering Chemistry, 2021, 204-213, Text

2. Biodegradable long-circulating polymeric nanospheres. Science 1994;363:1600-3, Text.

Click here to view an expanded list of hundreds of publications citing Creative PEGWorks products.

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