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PCL-PEG-COOH, PEG MW 5000 & PCL MW 2500

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PCL-PEG-COOH, PEG MW 5000 & PCL MW 2500

PCL PEG Acid
Catalog No: DCD-5k2500
Product Name: PCL-PEG-COOH, PEG MW 5000 & PCL MW 2500
In Stock: Yes
SKUProduct Name
DCD-5k2500-100mg
PCL-PEG-COOH, PEG MW 5000 & PCL MW 2500 - 100mg
$300.00
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DCD-5k2500-500mg
PCL-PEG-COOH, PEG MW 5000 & PCL MW 2500 - 500mg
$550.00
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+
DCD-5k2500-1g
PCL-PEG-COOH, PEG MW 5000 & PCL MW 2500 - 1g
$900.00
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+
Interested in Bulk Orders? Please contact us here

Description

PCL-PEG-COOH is an amphiphilic block copolymer consisting of a hydrophilic polyethylene glycol (PEG) and a hydrophobic polycaprolactone (PCL). The PEG polymer is capped a carboxylic acid COOH group. The hydrophobic block PCL terminates with a hydroxyl group. Biocompatible PEGylated copolymers with biodegradable polyester segments can be used to prepare core-shell micelles, nanoparticles and microspheres. The hydrolytic degradability of the polyester block depends on the molecular weight and the spacer between ester groups (lactide, glycotide or caprolactone). PEG-PCL with other MWs is also offered.

References

1) Selective eradication of human non-small cell lung cancer cells using aptamer-decorated nanoparticles harboring a cytotoxic drug cargo, Cell Death & Disease, 10, 702 (2019), DOI:  10.1038/s41419-019-1870-0

2) Targeted Nanoparticles Harboring Jasmine-Oil-Entrapped Paclitaxel for Elimination of Lung Cancer Cells, Int. J. Mol. Sci. 2021, 22, 1019. DOI: 10.3390/ijms22031019

3) Biodegradable long-circulating polymeric nanospheres. Science 1994;363:1600-3, Text.

Click here  to view an expanded list of hundreds of publications  citing Creative PEGWorks products.

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