PLA-PEG-COOH

PLA-PEG-COOH, Acid functionalized PEG-PLA is a useful reagent to prepare core-shell nanoparticles displaying acid groups on surface. The activated carboxylic acid is for conjugation with peptide or proteins bearing free amine. PEG-PLA is an amphiphilic AB diblock copolymer consisting of a hydrophilic block polyethylene glycol (PEG) and a hydrophobic block polylactic acid or polylactide (PLA). The PEG polymer is capped with a methyl ether group. The hydrophobic block terminates with a hydroxyl group. PEGylated copolymers with biodegradable and biocompatible polyester segments can be used to prepare core-shell micelles, nanoparticles and microspheres.

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PLA-PEG-COOH

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